| Item Type | Name |
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Concept
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Models, Molecular
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Concept
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Mice, Transgenic
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Concept
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Mammary Tumor Virus, Mouse
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Nude
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Concept
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Proportional Hazards Models
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Concept
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Models, Animal
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Concept
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Mice, Knockout
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Concept
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Mice
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Concept
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Hematologic Neoplasms
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Concept
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Disease Models, Animal
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Concept
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Mice, Mutant Strains
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Concept
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Models, Biological
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Academic Article
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The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.
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Academic Article
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Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
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Academic Article
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Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning.
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Academic Article
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Performance status and comorbidity predict transplant-related mortality after allogeneic hematopoietic cell transplantation.
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Academic Article
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Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease.
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Academic Article
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
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Academic Article
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The use of hypomethylating agents in the treatment of hematologic malignancies.
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Academic Article
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Successful allogeneic transplantation of patients with suspected prior invasive mold infection.
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Academic Article
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DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
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Academic Article
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TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
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Academic Article
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Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
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Academic Article
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The histone code and treatments for acute myeloid leukemia.
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Academic Article
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Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
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Academic Article
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Molecular biology. Preference by exclusion.
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Academic Article
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Pretreatment C-reactive protein is a predictor for outcomes after reduced-intensity allogeneic hematopoietic cell transplantation.
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Academic Article
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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
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Academic Article
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Dnmt3a is essential for hematopoietic stem cell differentiation.
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Academic Article
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HMGA2 levels in CML: reflective of miRNA gene regulation in a hematopoietic tumor?
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Academic Article
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Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
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Academic Article
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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
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Academic Article
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Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys.
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Academic Article
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Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
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Academic Article
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Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity.
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Academic Article
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Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
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Academic Article
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Defining the steps in a multistep mouse model for mammary carcinogenesis.
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Academic Article
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Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
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Academic Article
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Perspectives and future directions for epigenetics in hematology.
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Academic Article
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Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
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Academic Article
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Immune reconstitution after combined haploidentical and umbilical cord blood transplant.
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Academic Article
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Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.
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Academic Article
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Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes.
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Academic Article
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Cell characterization using a protein-functionalized pore.
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Academic Article
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Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
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Academic Article
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New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
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Academic Article
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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
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Academic Article
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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.
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Academic Article
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A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.
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Academic Article
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Large conserved domains of low DNA methylation maintained by Dnmt3a.
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Academic Article
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On the origin of leukemic species.
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Academic Article
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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
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Academic Article
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Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.
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Academic Article
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Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
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Academic Article
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Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
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Academic Article
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Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
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Academic Article
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Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival.
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Academic Article
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Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC).
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Academic Article
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Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients.
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Academic Article
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Genetic predisposition to leukemia and other hematologic malignancies.
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Academic Article
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How I diagnose and manage individuals at risk for inherited myeloid malignancies.
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Academic Article
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Germline ETV6 mutations and predisposition to hematological malignancies.
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Academic Article
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Genetic predisposition to hematologic malignancies: management and surveillance.
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Academic Article
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Recognition of familial myeloid neoplasia in adults.
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Academic Article
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Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
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Academic Article
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Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.
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Academic Article
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Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma.
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Academic Article
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Identifying patients with genetic predisposition to acute myeloid leukemia.
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Academic Article
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Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
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Academic Article
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Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.
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Academic Article
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MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.
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Academic Article
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Assessment of technical heterogeneity among diagnostic tests to detect germline risk variants for hematopoietic malignancies.
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Academic Article
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Regulation of telomeric function by DNA methylation differs between humans and mice.
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Academic Article
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Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.
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Academic Article
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Identifying potential germline variants from sequencing hematopoietic malignancies.
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Academic Article
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Identifying potential germline variants from sequencing hematopoietic malignancies.
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Academic Article
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Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer.
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Academic Article
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RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
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Academic Article
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Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model.
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Academic Article
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Germline predisposition to hematopoietic malignancies.
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Academic Article
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Inherited Susceptibility to Hematopoietic Malignancies in the Era of Precision Oncology.
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Academic Article
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The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
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Academic Article
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A practical guide to interpreting germline variants that drive hematopoietic malignancies, bone marrow failure, and chronic cytopenias.
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Academic Article
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Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies.
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Academic Article
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International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.
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Academic Article
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Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies.
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Academic Article
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Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.
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Grant
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The Role of DNMT3B in the DNA Methylation of Cancer Cells
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Academic Article
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Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
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Academic Article
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Donor-Derived Malignancy and Transplantation Morbidity: Risks of Patient and Donor Genetics in Allogeneic Hematopoietic Stem Cell Transplantation.
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Academic Article
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Insights into the Molecular Mechanisms of Genetic Predisposition to Hematopoietic Malignancies: The Importance of Gene-Environment Interactions.
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